Prove ADCC Activity

in real human skin

For therapies targeting mast cells, demonstrating antibody-dependent cell-mediated cytotoxicity (ADCC) in complex human tissue is essential.

Traditional in vitro assays provide limited context, leaving critical aspects of biological impact unclear.

HypoSkin® offers a solution
Our ex vivo human skin model lets you assess mast cell depletion in situ, offering a powerful, human-relevant platform to confirm the effects of engineered antibodies.
A recent study showed how HypoSkin helped validate Fc-enhanced anti-KIT antibodies for mastocytosis—revealing functional immune engagement at the tissue level.
Don’t just bind—deplete.

Download the study poster to see how HypoSkin can help you:

  • Demonstrate tissue-level ADCC
  • De-risk early immunotherapy development

Translate in vitro findings into clinical relevance

Please fill in the form below to access our poster.

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