Poster

Advancing mast cell research with a standardized human primary cell platform

Chenyan Wu1, Cyprien Pecalvel1, Anthony David1 and Nicolas Gaudenzio1,2
1Genoskin SAS, 2INSERM UMR1291 – CNRS UMR5051, University Toulouse III

Understanding mast cell activation in a human-relevant context

Mast cells play a central role in immune regulation, inflammation and allergic responses, making them highly relevant for immunology and safety research. Understanding their activation and mediator release is essential to characterize inflammatory pathways and evaluate the biological effects of new compounds, formulations, and therapeutic candidates.

Our human-relevant in vitro mast cells provide a controlled and reproducible approach to studying mast cell biology, degranulation, and mediator release. By generating mechanistic data in a human context, these immune cells support both academic and pharmaceutical research, from fundamental immunology to drug candidate evaluation, biologics, and safety testing.

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