News

New study model for injectable anti-psoriasis drugs A hi-tech psoriasis skin model to study drug efficacy To evaluate the efficacy of injectable anti-psoriasis drugs, the Genoskin team has designed a new test model that combines the InflammaSkin® and HypoSkin® technologies. Below you’ll find a proof-of-concept case study that illustrates the relevance of the new Hypo-InflammaSkin® model during efficacy studies of injectableRead more

3D imaging of cleared ex vivo human skin using light-sheet fluorescence microscopy The study was a collaborative project with Syntivia and The Institute for Advanced Technology in Life Sciences (ITAV). A promising approach for non-invasive imaging of human skin biopsies Human skin is rich in endogenous fluorophores that can be used as a source of optical contrast. However, 3D imagingRead more

DBV Technologies' epicutaneous immunotherapy tested using NativeSkin® ex vivo human skin Latest results to be presented at the AAAAI/WAO Joint Congress in Orlando The poster "Epicutaneous immunotherapy with peanut directly targets Langerhans cells in human skin" (n° 723, session  4204) will be presented at the American Academy of Allergy, Asthma & Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress in Orlando, Florida onRead more

Standardized ex vivo skin models for cosmetic testing Cosmetic testing is playing an increasingly important role in today’s cosmetic industry. The first cosmetic tests took place in 1933, after an eyelash darkening treatment blinded several women. In 1938, the U. S. Food and Drug Administration passed the Federal Food, Drug & Cosmetic (FD&C) Act to define stricter regulations for cosmetic productsRead more

New ex vivo perfusable vascularized human skin model for drug testing Perfusable vascularized skin for increased viability and optimal skin response Natural human skin contains a rich vascular network, which is essential for the transport and absorption of nutrients and drugs. However, a key drawback of currently engineered human skin models is their lack in vascularization. Recreating a vascularization inRead more