Overview of scientific publications
Examples of how our Models & Services can be used
Publications in scientific journals & magazines
Most Recent Scientific Publications
Genoskin aims to change drug development as we know it by using cutting-edge technology to make science move forward. Below you’ll find a list of publications that validate and/or use our unique technology and skin models for a wide range of applications. Simply click on the + sign to obtain more details and to access the publication of your choice.
September 2022 - Transcriptome Analysis of Particulate Matter 2.5-Induced Abnormal Effects on Human Sebocytes
- Transcriptome Analysis of Particulate Matter 2.5-Induced Abnormal Effects on Human Sebocytes
- Published in International Journal of Molecular Science – Int. J. Mol. Sci. 2022, 23(19), 11534; Published: 29 September 2022
(This article belongs to the Special Issue Environmental Toxicant Exposures and Metabolic Disease)- Hye-Won Na, Hyun Soo Kim,Hyunjung, Nari Cha,Young Rok Seo, Yong Deog Hong and Hyoung-June Kim.
- Published in International Journal of Molecular Science – Int. J. Mol. Sci. 2022, 23(19), 11534; Published: 29 September 2022
August 2022 - Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology
- Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology
- Published in Molecular Therapy Methods & Clinical Development – VOLUME 26, P441-458, SEPTEMBER 08, 2022
- Aurelien Lathuiliere, Remi Vernet, Emily Charrier, Muriel Urwyler, Olivier Von Rohr, Marie-Claude Belkouch, Valentin Saingier, Thomas Bouvarel, Davy Guillarme, Adrien Engel, Patrick Salmon, Thomas Laumonier, Julien Grogg, Nicolas Mach
- Published in Molecular Therapy Methods & Clinical Development – VOLUME 26, P441-458, SEPTEMBER 08, 2022
May 2022 - Mast cell–neuron axis in allergy
- Mast cell–neuron axis in allergy
- Published in Current Opinion in Immunology – Volume 77, August 2022, 102213 – available online as of May 20, 2022
- Nicolas Gaudenzio, Lilian Basso
- Published in Current Opinion in Immunology – Volume 77, August 2022, 102213 – available online as of May 20, 2022
January 2022 - Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment
- Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment
- Published in Nature – Scientific Reports – volume 12, Article number: 1501 (2022)
- Stefan Eirefelt, Martin Stahlhut, Naila Svitacheva, Martin A. Carnerup, Joel Mauricio Correa Da Rosa, David Adrian Ewald, Troels T. Marstrand, Mikkel Krogh-Madsen, Georg Dünstl, Kevin Neil Dack, Anna Ollerstam & Hanne Norsgaard
- Published in Nature – Scientific Reports – volume 12, Article number: 1501 (2022)
January 2022 - Polymethoxyflavones from Kaempferia parviflora ameliorate skin aging in primary human dermal fibroblasts and ex vivo human skin
- Polymethoxyflavones from Kaempferia parviflora ameliorate skin aging in primary human dermal fibroblasts and ex vivo human skin
- Published in Biomedicine & Pharmacotherapy – 2022 Jan;145:112461
- Wannita Klinngam, Phetploy Rungkamoltip, Saowarose Thongin, Jaruwan Joothamongkhon, Phattharachanok Khumkhrong, Mattaka Khongkow, Katawut Namdee, Surapun Tepaamorndech, Puxvadee Chaikul, Mayuree Kanlayavattanakul, Nattaya Lourith, Kitiya Piboonprai, Uracha Ruktanonchai, Udom Asawapirom, Tawin Iempridee
- Published in Biomedicine & Pharmacotherapy – 2022 Jan;145:112461
December 2021 - Barrier disruption, dehydration and inflammation: Investigation of the vicious circle underlying dry skin
- Barrier disruption, dehydration and inflammation: Investigation of the vicious circle underlying dry skin
-
- Published in International Journal of Cosmetic Science – 2021 Dec;43(6):729-737
- Cécile Bize, Erwan Le Gélébart, Alain Moga, Bruno Payré, Christine Garcia
- Published in International Journal of Cosmetic Science – 2021 Dec;43(6):729-737
December 2021 - A hypothetical skin sensitisation next generation risk assessment for coumarin in cosmetic products
- A hypothetical skin sensitisation next generation risk assessment for coumarin in cosmetic products
- Regulatory Toxicology and Pharmacology – 2021, 105075, ISSN 0273-2300
- G. Reynolds, J. Reynolds, N. Gilmour, R. Cubberley, S. Spriggs, A. Aptula, K. Przybylak, S. Windebank, G. Maxwell, M.T. Baltazar
- Regulatory Toxicology and Pharmacology – 2021, 105075, ISSN 0273-2300
November 2021 - A suspended layer additive manufacturing approach to the bioprinting of tri-layered skin equivalents
- A suspended layer additive manufacturing approach to the bioprinting of tri-layered skin equivalents
- Published in APL Bioengineering – 2021 Nov 30;5(4):046103.
- Richard J A Moakes, Jessica J Senior, Thomas E Robinson, Miruna Chipara, Aleksandar Atansov, Amy Naylor, Anthony D Metcalfe, Alan M Smith, Liam M Grover
- Published in APL Bioengineering – 2021 Nov 30;5(4):046103.
October 2021 - The anti-wrinkles properties of sodium acetylated hyaluronate
- The anti-wrinkles properties of sodium acetylated hyaluronate
- Published in Journal of Cosmetic Dermatology – 28 October 2021
- Marie Meunier MS, Amandine Scandolera PhD, Emilie Chapuis BS, Laura Lapierre BS, Jérôme Sandré MD, Gerhard Brunner PhD, Martin Lovchik PhD, Romain Reynaud MS
- Published in Journal of Cosmetic Dermatology – 28 October 2021
October 2021 - A proof-of-concept study utilising 2D NMR spectrometry for in situ characterisation and quantitation of key biomarkers and actives in tape stripped ex vivo human skin
- A proof-of-concept study utilising 2D NMR spectrometry for in situ characterisation and quantitation of key biomarkers and actives in tape-stripped ex vivo human skin
- Published in Talanta – October 2021
- Cameron Robertson, Nidhin Raj b, Robert Lucas b, Tomris Coban a, Adam Le Gresley
- Published in Talanta – October 2021
September 2021 - Clinical brightening efficacy and safety of Melasolv™ (3,4,5-trimethoxy cinnamate thymol ester, TCTE) in Southeast Asian women
- Clinical brightening efficacy and safety of Melasolv™ (3,4,5-trimethoxy cinnamate thymol ester, TCTE) in Southeast Asian women
- Published in Journal of Cosmetic Dermatology – 2021 Sep;20(9):2851-2859
- Seung Hun Kim, Byung Ryol Paik, Sung Hoon Lee, So Mi Lee, Mi Jin Kim, Eun Joo Kim, Chin Yong Leow, Changhui Cho, Won-Seok Park, Byung-Fhy Suh
- Published in Journal of Cosmetic Dermatology – 2021 Sep;20(9):2851-2859
July 2021 - Poster - Mitigation of Injection Site Reactions after Subcutaneous Administration of Dalcinonacog Alfa (DalcA) in Hemophilia B Using Preclinical Models
- Mitigation of Injection Site Reactions after Subcutaneous Administration of Dalcinonacog Alfa (DalcA) in Hemophilia B Using Preclinical Models
- Scientific Poster – ISTH 2021 Congress – Abstract PB0453
- N. Le Moan, L. Kelly, E. Merle, P. Descargues, N. Gaudenzio, H. Gagnon, A. Chatterji, G.E. Blouse
- Scientific Poster – ISTH 2021 Congress – Abstract PB0453
July 2021 - Poster - Assessing subcutaneous injection site reactions by leveraging immunocompetent human skin and artificial intelligence
- Assessing subcutaneous injection site reactions by leveraging immunocompetent human skin and artificial intelligence
- Scientific Poster – CRS 2021 Virtual Annual Meeting – July 25 to 29, 2021.
- Emeline Pagès, Emilie Braun, Eric Merle, Pascal Descargues, Nicolas Gaudenzio
- Scientific Poster – CRS 2021 Virtual Annual Meeting – July 25 to 29, 2021.
March 2021 - Thesis - Development, validation and characterization of a perfused ex vivo human skin model : FlowSkin
- Development, validation and characterization of a perfused ex vivo human skin model : FlowSkin
- PhD Thesis
- Emma Raude, Genoskin
- PhD Thesis
February 2021 - hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers
- hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers
- Published in International Journal of Molecular Sciences – 2021 Feb 11;22(4):1785
- Dulce Lima Cunha, Amanda Oram, Robert Gruber, Roswitha Plank, Arno Lingenhel, Manoj K Gupta, Janine Altmüller, Peter Nürnberg, Matthias Schmuth, Johannes Zschocke, Tomo Šarić, Katja M Eckl, Hans C Hennies
- Published in International Journal of Molecular Sciences – 2021 Feb 11;22(4):1785
February 2021 - Calcipotriol/Betamethasone Dipropionate Foam Inhibits Th17 Cytokine Secretion and Improves Epidermal Barrier Markers in a Human Th17 Skin Inflammation Model
- Calcipotriol/Betamethasone Dipropionate Foam Inhibits Th17 Cytokine Secretion and Improves Epidermal Barrier Markers in a Human Th17 Skin Inflammation Model
- Published in Dermatologic Therapy – 2021 Feb;11(1):265-274
- Paola Lovato, Li Jiang, Josephine Hebsgaard, David A Ewald, Hanne Norsgaard
- Published in Dermatologic Therapy – 2021 Feb;11(1):265-274
January 2021 - Challenges in Developing a Human Model System for Skin Microbiome Research
- Challenges in Developing a Human Model System for Skin Microbiome Research
- Published in Journal of Investigative Dermatology – 2021 Jan;141(1):228-231.e4.
- Peter J Larson, Derrick Chong, Elizabeth Fleming, Julia Oh
- Published in Journal of Investigative Dermatology – 2021 Jan;141(1):228-231.e4.
December 2020 - Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants
- Active neutrophil responses counteract Candida albicans burn wound infection of ex vivo human skin explants
- Published in Scientific Reports – 2020 Dec 11;10(1):21818
- Christin von Müller, Fionnuala Bulman, Lysett Wagner, Daniel Rosenberger, Alessandra Marolda, Oliver Kurzai, Petra Eißmann, Ilse D Jacobsen, Birgit Perner, Peter Hemmerich, Slavena Vylkova
- Published in Scientific Reports – 2020 Dec 11;10(1):21818
December 2020 - Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing
- Standalone or combinatorial phenylbutyrate therapy shows excellent antiviral activity and mimics CREB3 silencing
- Published in Science Advances – 2020 Dec 4;6(49):eabd9443
- Tejabhiram Yadavalli, Rahul Suryawanshi, Raghuram Koganti, James Hopkins, Joshua Ames, Lulia Koujah, Aqsa Iqbal, Krishnaraju Madavaraju, Alex Agelidis, Deepak Shukla
- Published in Science Advances – 2020 Dec 4;6(49):eabd9443
December 2020 - Photothermally Active Cryogel Devices for Effective Release of Antimicrobial Peptides: On-Demand Treatment of Infections
- Photothermally Active Cryogel Devices for Effective Release of Antimicrobial Peptides: On-Demand Treatment of Infections
- Published in ACS Applied Materials & Interfaces – 2020, 12, 51, 56805–56814
- Laura Chambre, Léa Rosselle, Alexandre Barras, Duygu Aydin, Aleksandra Loczechin, Suzan Gunbay, Rana Sanyal, Nadia Skandrani, Nils Metzler-Nolte, Julia Elisabeth Bandow, Rabah Boukherroub, Sabine Szunerits, and Amitav Sanyal
- Published in ACS Applied Materials & Interfaces – 2020, 12, 51, 56805–56814
November 2020 - Synthesis of Kisspeptin-Mimicking Fragments and Investigation of their Skin Anti-Aging Effects
- Synthesis of Kisspeptin-Mimicking Fragments and Investigation of their Skin Anti-Aging Effects
- Published in International Journal of Molecular Science – 2020 Nov; 21(22): 8439
- Kyung-Eun Lee, Sugyeong Jeong, Seok Kyun Yun, Seoyeon Kyung, Abadie Sophie, Sang Hyun Moh, Hyo Hyun Seo, Myeong Sam Park, Seunghyun Kang, and Hyeonju Yeo
- Published in International Journal of Molecular Science – 2020 Nov; 21(22): 8439
October 2020 - Development and characterization of a human Th17 driven ex vivo skin inflammation model
- Development and characterization of a human Th17‐driven ex vivo skin inflammation model
- Published in Experimental Dermatology – Oct. 2020;29(10):993-1003.
- Claire Jardet, Anthony David, Emilie Braun, Pascal Descargues, Jean-Louis Grolleau, Josephine Hebsgaard, Hanne Norsgaard, Paola Lovato
- Published in Experimental Dermatology – Oct. 2020;29(10):993-1003.
October 2020 - Biomimetic and estrogenic fibers promote tissue repair in mice and human skin via estrogen receptor β
- Biomimetic and estrogenic fibers promote tissue repair in mice and human skin via estrogen receptor β
- Published in Biomaterials – October 2020, PMID: 32521331
- Seungkuk Ahn, Christophe O Chantre, Herdeline Ann M Ardoña, Grant M Gonzalez, Patrick H Campbell, Kevin Kit Parker
- Published in Biomaterials – October 2020, PMID: 32521331
September 2020 - An ‘on-demand’ photothermal antibiotic release cryogel patch: evaluation of efficacy on an ex vivo model for skin wound infection
- An ‘on-demand’ photothermal antibiotic release cryogel patch: evaluation of efficacy on an ex vivo model for skin wound infection
- Published in Biomaterials Science – Sept. 2020 – 21(8), 5911-5919
- Rosselle, L., Cantelmo, A. R., Barras, A., Skandrani, N., Pastore, M., Aydin, D., Chambre, L., Sanyal, R., Sanyal, A., Boukherroub, R., Szunerits, S.
- Published in Biomaterials Science – Sept. 2020 – 21(8), 5911-5919
September 2020 - A novel skin brightening topical technology
- A novel skin brightening topical technology
- Published in Journal of Cosmetic Dermatology – 28 September 2020; 19: 3280– 3285
- Zoe Diana Draelos MD, Isabel Diaz BA, Aaron Cohen PhD, Junhong Mao PhD, Thomas Boyd PhD
- Published in Journal of Cosmetic Dermatology – 28 September 2020; 19: 3280– 3285
August 2020 - The anti-ageing effects of a natural peptide discovered by artificial intelligence
- The antiageing effects of a natural peptide discovered by Artificial Intelligence
- Published in International Journal of Cosmetic Science – August 2020, 42(4)
- Kathy Kennedy, Roi Cal, Rory Casey, Cyril Lopez, Soladis
- Published in International Journal of Cosmetic Science – August 2020, 42(4)
July 2020 - Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
- Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
- Published in Clinical Epigenetics volume 12, Article number: 105 (2020)
- Mariana Boroni, Alessandra Zonari, Carolina Reis de Oliveira, Kallie Alkatib, Edgar Andres Ochoa Cruz, Lear E. Brace & Juliana Lott de Carvalho
- Published in Clinical Epigenetics volume 12, Article number: 105 (2020)
April 2020 - Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation
- Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation
- Published in Frontiers in Cellular and Infection Microbiology – 2020 Apr 9; 10: 148
- Si En Poh, Joleen P. Z. Goh, Chen Fan, Wisely Chua, Shi Qi Gan, Priscilla Lay Keng Lim, Bhavya Sharma, David I. Leavesley, Thomas L. Dawson, Jr., and Hao Li
- Published in Frontiers in Cellular and Infection Microbiology – 2020 Apr 9; 10: 148
April 2020 - Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming
- Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming
- Published in Communications Biology volume 3, Article number: 188 (2020)
- Llorenç Solé-Boldo, Günter Raddatz, Sabrina Schütz, Jan-Philipp Mallm, Karsten Rippe, Anke S. Lonsdorf, Manuel Rodríguez-Paredes & Frank Lyko
- Published in Communications Biology volume 3, Article number: 188 (2020)
January 2020 - Mapping 2D- and 3D-distributions of metal/metal oxide nanoparticles within cleared human ex vivo skin tissues
- Mapping 2D- and 3D-distributions of metal/metal oxide nanoparticles within cleared human ex vivo skin tissues
- Published in NanoImpact – 2020 Jan;17:100208
- George J Touloumes, Herdeline Ann M Ardoña, Evan K Casalino, John F Zimmerman, Christophe O Chantre, Dimitrios Bitounis, Philip Demokritou, Kevin Kit Parker
- Published in NanoImpact – 2020 Jan;17:100208
January 2020 - Epidermal and Dermal Hallmarks of Photoaging are Prevented by Treatment with Night Serum Containing Melatonin, Bakuchiol, and Ascorbyl Tetraisopalmitate: In Vitro and Ex Vivo Studies
- Epidermal and Dermal Hallmarks of Photoaging are Prevented by Treatment with Night Serum Containing Melatonin, Bakuchiol, and Ascorbyl Tetraisopalmitate: In Vitro and Ex Vivo Studies
- Published in Dermatology & Therapy (Heidelberg) – 2020 Feb;10(1):191-202.
- Mridvika Narda, Anthony Brown, Béatrice Muscatelli-Groux, Jean A Grimaud, Corinne Granger
- Published in Dermatology & Therapy (Heidelberg) – 2020 Feb;10(1):191-202.
January 2020 - Translational drug discovery and development with the use of tissue-relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy
- Translational drug discovery and development with the use of tissue-relevant biomarkers: Towards more physiological relevance and better prediction of clinical efficacy
- Published in Experimental Dermatology – 2020 Jan;29(1):4-14
- Peter Florian, Klaus R Flechsenhar, Eckart Bartnik, Danping Ding-Pfennigdorff, Matthias Herrmann, Paul J Bryce, Frank O Nestle
- Published in Experimental Dermatology – 2020 Jan;29(1):4-14
January 2020 - Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression
- Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression
- Published in International Journal of Molecular Sciences – 2020 Jan; 21(1): 73
- Sekyoo Jeong, Seokjeong Yoon, Sungwoo Kim, Juyeon Jung, Myungho Kor, Kayoung Shin, Chaejin Lim, Hyo Sun Han, Haekwang Lee, Kyeong-Yong Park, Jinwan Kim, Hwa Jee Chung, and Hyun Jung Kim
- Published in International Journal of Molecular Sciences – 2020 Jan; 21(1): 73
Earlier Scientific Publications
2019 - An Efficient Means to Mitigate Skin Inflammaging by Inhibition of the NLRP3 Inflammasome and Nfkb Pathways: A Novel Epigenetic Mechanism
- An Efficient Means to Mitigate Skin Inflammaging by Inhibition of the NLRP3 Inflammasome and Nfkb Pathways: A Novel Epigenetic Mechanism
- Published in IFSCC Magazine 3 – 2019
- Hanane Chajra, Sandrine Delaunois, David Garandeau, Gaelle Saint-Auret, Marisa Meloni, Eunsun Jung, Mathilde Frechet
- Published in IFSCC Magazine 3 – 2019
November 2019 - Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
- Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
- Published in Cell Reports – November 26, 2019, Volume 29, Issue 9, P2546-2555.E4
- Tanay Bhatt, Aishwarya Bhosale, Bhavya Bajantri, Mruthyunjaya Swamy Mathapathi, Abrar Rizvi, Giorgio Scita, Amitabha Majumdar, Colin Jamora
- Published in Cell Reports – November 26, 2019, Volume 29, Issue 9, P2546-2555.E4
October 2019 - Improvements of both inflammation and skin barrier in a human Th17 skin inflammation model by topical treatment with fixed-dose combination calcipotriene/betamethasone dipropionate foam
- Improvements of both inflammation and skin barrier in a human Th17 skin inflammation model by topical treatment with fixed-dose combination calcipotriene/betamethasone dipropionate foam
- Published in Journal of the American Academy of Dermatology – October 01, 2019, Volume 81, Issue 4, Supplement 1, AB79
- Hanne Norsgaard, Paola Lovato, Li Jiang, Josephine Hebsgaard, David Adrian Ewald
- Published in Journal of the American Academy of Dermatology – October 01, 2019, Volume 81, Issue 4, Supplement 1, AB79
September 2019 - Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis
- Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis
- Published in Journal of Investigative Dermatology – 2019 Sep;139(9):1889-1897.e4.
- Laura Cau, Hidenari Takahara, Paul R Thompson, Guy Serre, Marie-Claire Méchin, Michel Simon
- Published in Journal of Investigative Dermatology – 2019 Sep;139(9):1889-1897.e4.
September 2019 - A human skin model to evaluate the protective effect of compounds against UVA damage
- A human skin model to evaluate the protective effect of compounds against UVA damage
- Published in International Journal of Cosmetic Science – 12 September 2019
- S. Abadie, P. Bedos, J. Rouquette
- Published in International Journal of Cosmetic Science – 12 September 2019
September 2019 - Poster - Scientific Visualisation of Skin Damage caused by Irritants in Human Skin
- Scientific Visualisation of Skin Damage caused by Irritants in Human Skin
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- Nidhin Raj, Robert Lucas, Sarah Coomasaru, Behfar Moghaddam, Ian Francis, Paul McGill – GlaxoSmithKline Consumer Healthcare, Weybridge, United Kingdom
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
September 2019 - Poster - Evaluation of pharmacological responses to subcutaneous injection of adalimumab in InflammaSkin®, a full-thickness human ex vivo skin model reproducing key features of psoriatic lesions
- Evaluation of pharmacological responses to subcutaneous injection of adalimumab in InflammaSkin®, a full-thickness human ex vivo skin model reproducing key features of psoriatic lesions
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- C. Jardet (Genoskin), E. Bartnik (Sanofi-Aventis Deutschland), D. Ding-Pfennigdorff (Sanofi-Aventis Deutschland), E. Braun (Genoskin), P. Descargues (Genoskin)
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
September 2019 - Poster - Ex vivo visualization and extended release from a dissolvable microarray
- Ex vivo visualization and extended release from a dissolvable microarray
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- K. T. Nielsen, A. H. Eriksson, M. F. Carlsen, K. M. Engel, J. Jansson, K. Petersson, M. A. Røpke, M. Bertelsen, P. Kemp –
LEO Pharma A/S, Ballerup, Denmark
- K. T. Nielsen, A. H. Eriksson, M. F. Carlsen, K. M. Engel, J. Jansson, K. Petersson, M. A. Røpke, M. Bertelsen, P. Kemp –
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
September 2019 - Poster - Preservation of human skin integrity and metabolism during 10 days in culture with NativeSkin® system
- Preservation of human skin integrity and metabolism during 10 days in culture with NativeSkin® system
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- E. Raude (Genoskin), E. Pagès (Genoskin), M. Pastore (Genoskin), P.-O. Cuoc (Promega), L. Malaquin (LAAS-CNRS), P. Descargues (Genoskin)
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
September 2019 - Poster - Bacterial infection and wound healing in an ex vivo human skin model
- Bacterial infection and wound healing in an ex vivo human skin model
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
- E. Pagès (Genoskin), M. Pastore (Genoskin), L. Rosselle (TissueAegis), A. Barras (UMR 8520 – IEMN), N. Skandrani (TissueAegis), A.R. Cantelmo (INSERM U1003), R. Boukherroub (UMR 8520 – IEMN), P. Descargues (Genoskin), S. Szunerits (UMR 8520 – IEMN)
- Scientific Poster presented at the 2019 Congress of the European Society for Dermatological Research (ESDR) – September 18-21, 2019
August 2019 - Near-infrared light activable hydrogels for metformin delivery
- Near-infrared light activable hydrogels for metformin delivery
- Published in Nanoscale – 2019 Aug 29;11(34):15810-15820
- Li Chengnan, Quentin Pagneux, Anna Voronova, Alexandre Barras, Amar Abderrahmani, Valérie Plaisance, Valerie Pawlowski, Nathalie Hennuyer, Bart Staels, Lea Rosselle, Nadia Skandrani, Musen Li, Rabah Boukherroub, Sabine Szunerits
- Published in Nanoscale – 2019 Aug 29;11(34):15810-15820
July 2019 - The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity
- The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity
- Published in Journal of Investigative Dermatology – July 1, 2019, Volume 139, Issue 7, P1430-1438
- Marie Reynier, Sophie Allart, Dominique Goudounèche, Alain Moga, Guy Serre, Michel Simon, Corinne Leprince
- Published in Journal of Investigative Dermatology – July 1, 2019, Volume 139, Issue 7, P1430-1438
June 2019 - The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes
- The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes
- Published in Journal of Investigative Dermatology – 2019 Jun;139(6):1395-1397.
- Géraldine Albérola, Jens-Michael Schröder, Carine Froment, Michel Simon
- Published in Journal of Investigative Dermatology – 2019 Jun;139(6):1395-1397.
December 2018 - Melatonin, bakuchiol and ascorbyl tetraisopalmitate synergize to modulate gene expression and restore Hypoxia-Inducible Factor 1 signaling in UV-exposed skin
- Melatonin, bakuchiol and ascorbyl tetraisopalmitate synergize to modulate gene expression and restore Hypoxia-Inducible Factor 1 signaling in UV-exposed skin
- Published in Cellular and Molecular Biology – 2018 Dec 31;65(8):39-47.
- Mridvika Narda, Anthony Brown, Daniel Pérez-Cremades, José Luís García-Giménez, Corinne Granger
- Published in Cellular and Molecular Biology – 2018 Dec 31;65(8):39-47.
December 2018 - Poster - A fully functional ex vivo human skin model to study human skin microbiome
- A fully functional ex vivo human skin model to study human skin microbiome
- Scientific Poster presented at the BacTouBac meeting of the Paul Sabatier University in Toulouse – December 11 & 12, 2018
- B. Coupe (Vaiomer), M. Pastore (Genoskin), E. Pagès (Genoskin), E. Braun (Genoskin), A. Broha (Vaiomer), P. Descargues (Genoskin)
- Scientific Poster presented at the BacTouBac meeting of the Paul Sabatier University in Toulouse – December 11 & 12, 2018
October 2018 - Phenotypic and lipidomic characterization of primary human epidermal keratinocytes exposed to simulated solar UV radiation
- Phenotypic and lipidomic characterization of primary human epidermal keratinocytes exposed to simulated solar UV radiation
- Published in Journal of Dermatological Science – 2018 Oct;92(1):97-105.
- Núria Dalmau, Nathalie Andrieu-Abadie, Romà Tauler, Carmen Bedia
- Published in Journal of Dermatological Science – 2018 Oct;92(1):97-105.
October 2018 - Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin
- Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin
- Published in Molecular Basis of Disease – Biochimica et Biophysica Acta (BBA) – 2018 Oct;1864(10):3268-3280.
- Dániel Horváth, Adrienn Sipos, Evelin Major, Zoltán Kónya, Róbert Bátori, Dóra Dedinszki, Attila Szöll Si, István Tamás, Judit Iván, Andrea Kiss, Ferenc Erd di, Beáta Lontay
- Published in Molecular Basis of Disease – Biochimica et Biophysica Acta (BBA) – 2018 Oct;1864(10):3268-3280.
May 2018 - 3D imaging of cleared human skin biopsies using light-sheet microscopy: A new way to visualize in-depth skin structure
- 3D imaging of cleared human skin biopsies using light-sheet microscopy: A new way to visualize in-depth skin structure
- Published in Skin Research & Technology – 2018 May;24(2):294-303.
- S Abadie, C Jardet, J Colombelli, B Chaput, A David, J-L Grolleau, P Bedos, V Lobjois, P Descargues, J Rouquette
- Published in Skin Research & Technology – 2018 May;24(2):294-303.
May 2018 - Poster - 3D imaging of cleared ex vivo normal human skin, skin appendages and psoriasiform skin lesion using light-sheet microscopy
- 3D imaging of cleared ex vivo normal human skin, skin appendages and psoriasiform skin lesion using light-sheet microscopy
- Scientific Poster presented at the International Investigative Dermatology (IID) 2018 Meeting – 16-19 May 2018
- C. Jardet (Genoskin), S. Abadie (Syntivia), M. Pastore (Genoskin), J. Colombelli (Advanced Digital Microscopy – IRB), B. Chaput (CHU Toulouse Rangueil), A. David (Genoskin), J.-L. Grolleau (CHU Toulouse Rangueil), P. Bedos (Syntivia), V. Lobjois (ITAV), P. Descargues (Genoskin), J. Roquette (ITAV)
- Scientific Poster presented at the International Investigative Dermatology (IID) 2018 Meeting – 16-19 May 2018
May 2018 - Poster - NativeSkin®, an immunocompetent human skin model to study antigen uptake and processing by Langerhans cells
- NativeSkin®, an immunocompetent human skin model to study antigen uptake and processing by Langerhans cells
- Scientific Poster presented at the International Investigative Dermatology (IID) 2018 Meeting – 16-19 May 2018
- E. Pagès (Genoskin), L. Mondoulet (DBV Technologies), E. Bonnefont (Genoskin), E. Braun (Genoskin), V. Dhelft (DBV Technologies), C. Dupont (Hôpital Necker, Université Paris-Descartes), H. Sampson (DBV Technologies), P. Descargues (Genoskin)
- Scientific Poster presented at the International Investigative Dermatology (IID) 2018 Meeting – 16-19 May 2018
March 2018 - Poster - Epicutaneous immunotherapy with peanut directly tragets Langerhans cells in human skin
- Epicutaneous immunotherapy with peanut directly tragets Langerhans cells in human skin
- Scientific Poster presented at the American Academy of Allergy, Asthma & Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress on March 2-5, 2018.
- Vincent Dioszeghy, Emeline Pages, Christophe Dupont, Hugh A. Sampson, Pascal Descargues, Lucie Mondoulet
- Scientific Poster presented at the American Academy of Allergy, Asthma & Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress on March 2-5, 2018.
January 2018 - Poster - Evaluation of local inflammatory reactions following subcutaneous injection of a pro-inflammatory cocktail in a fully human ex vivo skin model
- Evaluation of local inflammatory reactions following subcutaneous injection of a pro-inflammatory cocktail in a fully human ex vivo skin model
- Scientific Poster presented at DECHEMA Advances in Medical Biology Seminar – January 30 to 31, 2018
- C. Jardet (Genoskin), E. Pagès (Genoskin), E. Raude (Genoskin), F. Seeliger (AstraZeneca), L. Brandén (AstraZeneca), E. Braun (Genoskin), M. Ingelsten (LAAS-CNRS), P. Descargues (Genoskin)
- Scientific Poster presented at DECHEMA Advances in Medical Biology Seminar – January 30 to 31, 2018
September 2017 - Oxidative damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail
- Oxidative damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail
- Published in Scientific Reports – 06 September 2017
- Marlène Dezest, Mickael Le Bechec, Laurent Chavatte, Valérie Desauziers, Benoît Chaput, Jean-Louis Grolleau, Pascal Descargues, Carine Nizard, Sylvianne Schnebert, Sylvie Lacombe & Anne-Laure Bulteau
- Published in Scientific Reports – 06 September 2017
September 2017 - Poster - Evaluation of pharmacological responses in a fully human ex vivo skin model following in situ T cell activation with Th17/Th1 psoriasis-like phenotype
- Evaluation of pharmacological responses in a fully human ex vivo skin model following in situ T cell activation with Th17/Th1 psoriasis-like phenotype damage and impairment of protein quality control systems in keratinocytes exposed to a volatile organic compounds cocktail
- Scientific Poster presented at the 47th Annual Meeting of the European Society for Dermatological Research (ESDR) – September 27 to 30, 2017
- P. Lovato (LEO Pharma), C. Jardet (Genoskin), E. Pagès (Genoskin), H. Norsgaard (LEO Pharma), P. Descargues (Genoskin)
- Scientific Poster presented at the 47th Annual Meeting of the European Society for Dermatological Research (ESDR) – September 27 to 30, 2017
June 2017 - SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes
- SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes
- Published in BMC Dermatology – 10 June 2017
- Leslie Calapre, Elin S. Gray, Sandrine Kurdykowski, Anthony David, Pascal Descargues & Mel Ziman
- Published in BMC Dermatology – 10 June 2017
January 2017 - Mechanistic insights into the impact of Cold Atmospheric Pressure Plasma on human epithelial cell lines
- Mechanistic insights into the impact of Cold Atmospheric Pressure Plasma on human epithelial cell lines
- Published in Scientific Reports – 25 January 2017
- Marlène Dezest, Laurent Chavatte, Marion Bourdens, Damien Quinton, Mylène Camus, Luc Garrigues, Pascal Descargues, Stéphane Arbault, Odile Burlet-Schiltz, Louis Casteilla, Franck Clément, Valérie Planat & Anne-Laure Bulteau
- Published in Scientific Reports – 25 January 2017
2016 - In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics
- In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics
- Published in Skin Pharmacology & Physiology – 2016;29(6):300-308.
- Bart Desmedt, Gamze Ates, Patricia Courselle, Jacques O De Beer, Vera Rogiers, Benoit Hendrickx, Eric Deconinck, Kristien De Paepe
- Published in Skin Pharmacology & Physiology – 2016;29(6):300-308.
November 2016 - Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase
- Integrating targeted gene expression and a skin model system to identify functional inhibitors of the UV activated p38 MAP kinase
- Published in Photochemical & Photobiological Sciences – 2016 Nov 30;15(12):1468-1475.
- Amaal Abrahams, Nicolas Mouchet, Nicolas Gouault, Françoise Lohézic Le Dévéhat, Myriam Le Roch, Isabelle Rouaud, David Gilot, Marie-Dominique Galibert
- Published in Photochemical & Photobiological Sciences – 2016 Nov 30;15(12):1468-1475.
October 2016 - Thesis - Development of a human ex vivo melanoma model based on the implantation of tumor spheroids into skin explants
- Development of a human ex vivo melanoma model based on the implantation of tumor spheroids into skin explants
- PhD Thesis
- Claire Jardet, Genoskin COO
- PhD Thesis
May 2016 - Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo
- Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo
- Published in BMC Dermatology – 2016 May 26;16(1):6.
- Leslie Calapre, Elin S Gray, Sandrine Kurdykowski, Anthony David, Prue Hart, Pascal Descargues, Mel Ziman
- Published in BMC Dermatology – 2016 May 26;16(1):6.
October 2015 - In vitro and in vivo dermal absorption assessment of acetyl aspartic acid: a compartmental study
- In vitro and in vivo dermal absorption assessment of acetyl aspartic acid: a compartmental study
- Published in International Journal of Cosmetic Science – 2015 Oct;37 Suppl 1:34-40.
- L Duracher, L Visdal-Johnsen, A Mavon
- Published in International Journal of Cosmetic Science – 2015 Oct;37 Suppl 1:34-40.
October 2015 - Safety assessment of a novel active ingredient, acetyl aspartic acid, according to the EU Cosmetics Regulation and the Scientific Committee on Consumer Safety guidelines
- Safety assessment of a novel active ingredient, acetyl aspartic acid, according to the EU Cosmetics Regulation and the Scientific Committee on Consumer Safety guidelines
- Published in International Journal of Cosmetic Science – 2015 Oct;37 Suppl 1:21-7.
- P Daly, G Moran
- Published in International Journal of Cosmetic Science – 2015 Oct;37 Suppl 1:21-7.
March 2015 - A Novel Explant Model for Skin Delivery Assessment
- A Novel Explant Model for Skin Delivery Assessment
- Published in Cosmetics & Toiletries – March 1, 2015
- Lucie Duracher, PhD; Lene Visdal-Johnsen, PhD; and Alain Mavon, PhD; Sandrine Kurdykowski, PhD; and Pascal Descargues, PhD
- Published in Cosmetics & Toiletries – March 1, 2015
March 2015 - Human Skin Models for Research Applications in Pharmacology and Toxicology: Introducing NativeSkin®, the “Missing Link” Bridging Cell Culture and/or Reconstructed Skin Models and Human Clinical Testing
- Human Skin Models for Research Applications in Pharmacology and Toxicology: Introducing NativeSkin®, the “Missing Link” Bridging Cell Culture and/or Reconstructed Skin Models and Human Clinical Testing
- Published in Applied In Vitro Toxicology – 6 March 2015 Vol. 1, No.1
- Bart De Wever, Sandrine Kurdykowski, and Pascal Descargues
- Published in Applied In Vitro Toxicology – 6 March 2015 Vol. 1, No.1
October 2014 - Calcipotriol counteracts betamethasone-induced decrease in extracellular matrix components related to skin atrophy
- Calcipotriol counteracts betamethasone-induced decrease in extracellular matrix components related to skin atrophy
- Published in Archives of Dermatological Research – 2014 Oct;306(8):719-29.
- Hanne Norsgaard, Sandrine Kurdykowski, Pascal Descargues, Tatiana Gonzalez, Troels Marstrand, Georg Dünstl, Mads Røpke
- Published in Archives of Dermatological Research – 2014 Oct;306(8):719-29.
