Toxicity Assessment

Understanding Local Tolerancein Drug DevelopmentIn the ever-evolving field of drug development, ensuring the safety and efficacy of new therapeutic agents is paramount. A crucial aspect of this safety evaluation is the assessment of cytotoxicity – the potential of substances to harm or destroy cells. Particularly in the realm of skin cytotoxicity, the concept of Local Tolerance, especially in the contextRead more

Redefining Local Toxicity AssessmentPart 2 - The Role of Animal-Free Non-Clinical Platforms in Drug Development. In the realm of non-clinical animal-free platforms, a transformative shift is unfolding in response to the challenges posed by drug-induced adverse reactionsa predominant factor leading to the discontinuation of drug development projects and the withdrawal of drugs from the market1. The imperative for accurate, ethical,Read more

Redefining Local Toxicity AssessmentPart 1 - The Role of Animal-Free Non-Clinical Platforms in Drug DevelopmentIn the intricate world of drug development, the quest for precision, safety, and efficacy is unending.Traditional toxicity assessment methods using animal models, while historically significant, have shown discernible limitations in their predictability of human responses. As the biotech and pharma sectors continue to push the boundariesRead more